12/31/2023 0 Comments Latuda copay cardElevated blood sugar, fats, or cholesterol.People taking drugs or substances that will strongly interfere with the body’s metabolism of lurasidone.People who are allergic to lurasidone or any of its inactive ingredients.Latuda comes with an FDA black-box warning that it is not to be used to treat dementia-related psychosis because of the risk of death or stroke. Unfortunately, some serious side effects may take longer to resolve and others, such as tardive dyskinesia, may be irreversible. Most minor and some serious side effects will begin to resolve about that time. After long-term treatment, Latuda will take about two to four days to completely clear from the body. Side effects may last as long as Latuda is being taken, but some minor side effects may decrease over time. A healthcare provider may prescribe Parkinson’s medications to alleviate antipsychotic withdrawal. Other symptoms of antipsychotic withdrawal include involuntary movements, twitching, slow movements, compulsion to move, nausea, vomiting, diarrhea, and stomach pain. If the patient has been symptom-free for some time, the return of symptoms can seem worse than before treatment. The most common withdrawal symptom when discontinuing antipsychotics is symptom rebound. Nonetheless, the American Psychiatric Association recommends reducing the dose by 10% each month when discontinuing antipsychotic medications to reduce the risk of withdrawal or symptom rebound. Those that do may experience mild or severe withdrawal symptoms. However, antipsychotic drugs that work in the same way as Latuda, called dopamine antagonists, can cause withdrawal symptoms when discontinued, but not all patients will experience withdrawal effects when discontinuing atypical antipsychotics. Neither the manufacturer nor the Physician’s Desk Reference specify withdrawal as a side effect or recommend a tapered dosing regimen when discontinuing Latuda. There are no studies or clinical trials focusing on withdrawal symptoms of Latuda, though there are reports of Latuda withdrawal. However, the manufacturer advises that weight be monitored carefully when taking Latuda. As a result, side effects such as weight gain, tremor, and orthostatic hypotension are less common and less severe than with other antipsychotic drugs. This is due to Latuda’s weak effects on certain types of nerve receptors that other antipsychotic medications do interact with. What all this means is that the risk of weight gain when taking Latuda is lower than it is with other antipsychotics. Around 4.8% of patients in this trial gained more than 7% of body weight versus about 3.3% who were taking a placebo. However, according to the same clinical trial listed above, Latuda scores on the low end, causing an average weight gain of about one pound in the short-term and about two pounds in the long-term (one year). Latuda weight gainĪntipsychotic medications typically cause metabolic changes and weight gain as unwanted side effects, but the extent of weight gain varies by drug. For this reason, Latuda is not approved to treat dementia-related psychosis. However, the manufacturer, Sunovion Pharmaceuticals Inc., advises that Latuda be used with caution in patients with a history of seizures.įinally, Latuda raises the risk of stroke and death in patients over the age of 65 with dementia-related psychosis. In clinical trials, patients taking Latuda had a very low rate of seizures, making Latuda a low-risk drug for inducing seizures. Many antipsychotic medications lower the “seizure threshold,” putting patients at an increased risk for seizures due to other causes.
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